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NucleoCounter® NC-202™

Automated cell counter

Any culture – Any user – Anywhere

  • Consistency across instruments, users and sites
  • Eliminate human errors with Via2-Cassette™
  • Monitor production runs with NEW DebrisIndex™
  • Increased cell counting range: No more dilutions
  • Scalable system with 21 CFR Part 11 / GMP-ready software
  • Personal support by our dedicated experts

NucleoCounter® NC-202™ automated cell counter

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The NucleoCounter® NC-202™ automated cell counter is our 3rd generation cassette-based instrument. Featuring improved hardware and the new user-friendly NC-View™ software, we take precision, speed, and data management of cell counting to new levels.

Consistency between instruments, users and sites

The NucleoCounter® NC-202™ is the most precise automated cell counter on the market: The combined inter-operator/inter-instrument variation is typically 5 – 10%. We achieve superior performance through high quality components that are stable over time, and advanced factory calibrations. Consequently, you obtain identical results with any cell sample, recorded by any user, anywhere in the world.

Consistency of NucleoCounter® NC-202™ automated cell counter shown in graph

Consistency of NucleoCounter® NC-202™ automated cell counter with different users

NEW DebrisIndex™ – Monitor Production Runs

The all new DebrisIndex™ is a measurement of culture debris build-up. Debris negatively affects downstream filtering and purifications steps, so a direct measurement of debris facilitates better process development parameters. The DebrisIndex™ can also be used as an additional read-out of cell culture health. Together with data for standard biological parameters such as live and dead cells, cell diameter, aggregation etc., the DebrisIndex™ gives an accurate picture of the overall cell culture performance. When correlated with data for production output, the DebrisIndex™ sets the specifications for when to initiate the next step. The DebrisIndex™ can also increase with culture contamination by e.g. bacteria or fungi, making for an additional purity parameter.

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21 CFR Part 11/GMP-ready software

The NC-View™ software is compatible with 21 CFR Part 11/GMP guidelines and can be integrated into your clinical workflow. This allows for painless transfer of protocols involving the NucleoCounter® NC-202™ automated cell counter, across departments and applications from R&D through to QC.

Standardized Cell Counting Workflow – Easy to Use

 

NucleoCounter® NC-202™ standardized cell counting workflowWe offer an easy-to-use workflow: Just Load sample – press RUN – get data. The unique Via2-Cassette™ combines sample aspiration, cell staining and counting chamber-loading into one simple step. Insert the loaded Via2-Cassette™ into the NucleoCounter® NC-202™ and press RUN. The NC-View™ software will automatically acquire fluorescent images, identify cells and present the data. The standardized workflow ensures handling interference is negligible for the highest data robustness.

The NucleoCounter® NC-202™ automated cell counter offers the best cell counting precision on the market, with full linearity up to 1×107 cells/ml. This makes lab workflow easy, by reducing the need for sample dilution ahead of measurements.

NucleoCounter® NC-202™ simple worklow

A safe, non-toxic cell counting system

A closed cell counting system that uses self-contained disposable cassettes, helps the user stay protected when handling samples. No pipettes, no exposure to (toxic) reagents, and minimal clean-up make the NucleoCounter® system a safe option.

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Personal support by our dedicated experts

ChemoMetec is fully committed to the success and satisfaction of our customers. We offer training, applications support and dedicated field service teams to ensure our customers achieve optimal instrument performance and the best quality results in an easy and simple manner.

NucleoCounter NC-202 in the lab

Conventional cellcounting versus counting with NucleoCounter® NC-202™

What’s NEW – NucleoCounter® NC-202™
Automated cell counter

  • Analysis time only 30 seconds/sample
  • Improved light sources for greater signal-to-noise ratio and dynamic range
  • Electromechanical cassette slot for easy operation
  • DebrisIndex™ monitors cell culture health and bioreactor production runs
  • Broader linearity range: Count samples up to 1×107 cells/ml
  • Instrument Service Plan: Keep your instrument up-to-date
  • Automatic data quality checks for sample artefacts
  • Tech Specifications
  • Downloads
  • Consumables

Tech Specifications

Technical Specifications
Loading volume App. 60 μl loaded into the Via2-Cassette™
Analyzed volume 1.35 μl (volume-calibrated Via2-Cassette™)
Analysis time 30 seconds
Optimal range 5×104 to 1×107 cells/ml
Size 38 × 26 × 22 cm (W × H × D)
Weight 4.9 kg (10.8 lb)
Software NC-View™

Downloads

Brochures
No. Brochure Name Download
990-0260 NucleoCounter® NC-202™ Open PDF
990-0400 Service Plan Open PDF
User Guides
No. Guide Name Download
991-2023 NucleoCounter® NC-202™ Quick User Guide Open PDF
991-2020 NucleoCounter® NC-202™ Instrument User Guide Open PDF
991-2022 NC-View™ Software User Guide Open PDF
Application Notes
No. Assay Name Download
994-2026 Cell Count and Viability – Mammalian Cells Open PDF
994-2028 Cell Count and Viability – Aggregated Cells Open PDF
994-2024 PQ Testing for NC-202 Open PDF
994-2034 Cell Count and Viability – Microcarriers Open PDF
994-2035 Cell Count and Viability – Chicken Embryo Fibroblasts Open PDF
994-2036 Cell Count and Viability – Insect Cells Open PDF
994-2037 Cell Count and Viability – PBMCs Open PDF
994-0303 Cell Count and Viability – Yeast Cells Open PDF
Documentation
No. Document Name Download
994-2029 NucleoCounter® NC-202™ Performance data Open PDF
994-2030 Effects of sample concentration on cell counting variation NucleoCounter® NC-202™ Open PDF

Consumables

Consumables Accessories
Via2-Cassette™, 1 Box (100 pcs.) Laptop Stand for NC-202™

*Note: Purchase the Consumables and Accessories directly in our WebShop.

Find Via2-Cassette™ COAs in the webshop

Instruments

Xcyto® 5
NucleoCounter® NC-3000™ NucleoCounter® NC-202™ NucleoCounter® NC-200™ NucleoCounter® SP-100™ NucleoCounter® YC-100™

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