Listen to the Cell Culture Dish’s podcast with our Product Manager, Christian Berg
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The new episode of the Cell Culture Dish’s podcast saw our Global Product Manager, Christian Berg, discussing the importance of standardizing cell counting for successful experiments. This is an essential consideration for:
- Manufacturing biologics (biosimilars) e.g. CHO cells
- Cell therapy and virus manufacturing, e.g. microcarrier cultures
- Bioassays for drug testing
- Research teams with a multitude of cell types
Often overlooked, cell density influences cell signaling, which affects cell culture growth and production, making it a critical parameter to control a successful manufacturing process. When tightly controlled, cell culture and manufacturing standardization leads to higher success rates and savings in time and cost.
The main challenges when standardizing cell counting are:
- VARIATION: Inaccuracies in human and instrumental procedures
- STABILITY: Ensuring instrument up-time is maximized
- DATA MANAGEMENT: Reliable transfer of processes across sites
Cell manufacturing in several industries is starting to include robotics and reliable manufacturing execution systems (MES). A full integration of cell counting instruments with industry processes will allow for better standardization and ultimately better products for the pharmaceutical and life science industries.
Consistency between instruments, users and sites
The NucleoCounter® NC-202™ is the most precise automated cell counter on the market: The combined inter-operator/inter-instrument variation is typically 5 – 10%. We achieve superior performance through high quality components that are stable over time, and advanced factory calibrations. Consequently, you obtain identical results with any cell sample, recorded by any user, anywhere in the world.