Adhering to 21 CFR Part 11 is essential in cGMP environments. This webinar describes how ChemoMetec solves the challenges…
Adhering to 21 CFR part 11 is essential in cGMP environments
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NucleoCounter® NC-203™
Accurate, Fast & Integration-Ready
- Combined Brightfield/Fluorescence based imaging.
- Consistent results across instruments & operators.
- No sample contact with the instrument.
- Reliable differentiation between cells and debris.
- 21 CFR Part 11 Ready Software.
- API-driven automated data retrieval.
The NucleoCounter® NC-203™ is a high-precision cell counter designed to deliver accurate, fast, and consistent analysis of complex cell samples.
As cell types, (co-)culture conditions, and cell-based fill-finish products become increasingly complex, more versatile imaging information is required to maintain a high level of analytical accuracy.
As cell types, (co-)culture conditions, and cell-based fill-finish products become increasingly complex, more versatile imaging information is required to maintain a high level of analytical accuracy.
The NucleoCounter® NC-203™ combines ChemoMetec’s proven cassette-based technology with brightfield imaging, enhancing cell detection and enabling robust differentiation between cells and non-cellular artifacts.
Used together with the Via3-Cassette™, the NC-203™ creates a closed cell-counting system that helps protect users when handling samples. No pipettes, no exposure to (toxic) reagents, and minimal clean-up make the NucleoCounter® system a safe and user-friendly solution.
The NucleoCounter® NC-203™ is developed in alignment with the XcytoMatic® platform, ensuring consistency across ChemoMetec’s analytical solutions. A key part of this alignment is the use of XM-View™, the shared software platform across the XcytoMatic® series.
XM-View™ also provides API access for the NC-203™, improving traceability, reducing manual data handling, and ensuring that cell-counting data can be captured, structured, and integrated seamlessly into broader data-management architectures.
| Cell types | Mammalian cell types (CHO, HEK, A3 and more…), primary cell type (PBMCs, Leukopak) |
| Software | XM-View™ Software |
| Consumable(s) | Via3-Cassette™ |
| Analysis time | 30 seconds |
| Loading volume | 60 µl |
| Analyzed volume | 1.35 µl (individually volume-calibrated Via3-Cassette™) |
| Counting range | 5 × 10⁴ – 1 × 10⁷ cells/ml |
| Excitation (nm) | 3 LED light sources with peak wavelengths at 365 nm, 505 nm, 430 nm |
| Emission (nm) | A single dual-band emission filter: 410–460 nm and 540–650 nm |
| Optics | Lens with ×2.1 magnification, 2/3” CMOS |
| Product Number |
900-0203 |
| Size | H 23 cm, W 40 cm, D 25 cm |
| Weight | 4.9 kg |
| Operation and storage conditions | Maximum relative humidity 80% up to 31 °C, decreasing linearly to 65% at 35 °C; minimum temperature 15 °C |
| Supply voltage | 24 VDC (100–240 V~ 50–60 Hz) |
| Power consumption | 7/20 W (Ready mode/peak) |
Sampling Devices, Reagents & Test Kits for the NucleoCounter® NC-203™
| Product type | Product No. | Product name |
| Sampling Devices | 941-0026 | Via3-Cassette™ |
| Reagents | 910-0010 | Lysis 1 Acidic Lysis Buffer |
| Software | 950-0040 | XM-View™ Software |
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