NucleoCounter® YC-100™

Automated Yeast Cell Counter

  • Excellent reproducibility
  • Safe sample handling and disposal
  • Dedicated assay for aggregated cells
  • Easy to operate
  • Analysis in 30 seconds
  • No cleaning or calibration required

The NucleoCounter® YC-100™ is the most precise automated yeast cell counter on the market. Perfect for the brewing industry, it is used to count cells in pitching yeast, yeast in suspension, and dry yeast. It measures the total cell count and viability of yeast cells in suspension.

This automated yeast cell counter features a camera and an integrated fluorescence microscope designed to detect signals from the fluorescent dye, propidium iodide (PI) when bound to DNA. Results from this instrument represent either total or non-viable cell concentration, depending on the sample preparation.

Read more about the Cassette technology

Application type(s) Cell count & viability analysis
Cell type(s) Pitching yeast, yeast in suspension, dry yeast
Software NucleoView™ for documentation and presentation (optional)
Consumable(s) NucleoCassette™
Capacity (Analysis time) 30 seconds
Loading volume 60 μl
Analysis volume 1.0 μl (NucleoCassette™)
Optimal range 5×104 to 6×106 cells/ml
Staining dye(s) Propidum iodide (PI)
Optics CCD camera
Data output Data numbers
Data export formats .cm, .csv, .pdf, .cmpp, .bmp, .acs, .fcs
Product Number
40 × 23 × 25 cm (W × H × D)
4.9 kg (10.8 lb)
Supply voltage
24VDC (100-240V ~ 50-60Hz)
External printer for documentation (optional)
Sampling Devices, Reagents & Test Kits for the NucleoCounter® YC-100™ Automated Yeast Cell Counter.


Product type Product No. Product name
Sampling Devices 941-0002 NucleoCassette™
Software NucleoView™
Solutions 910-0300 Reagent Y100 Lysis Buffer, 500 ml
Accessories 930-0002 Power Supply: NucleoCounter® NC-100™, YC-100™, SP-100™, SCC-100™
929-0008 Short LID Green
931-0001 USB Cable, 2 Meters
911-0003 Dispenser 1 – 10 ml
929-0001 Bottle Stand
939-0012 LTS Paper for PCNEOS-S2BN
911-0013 NucleoCounter® Cleaning Kit