CHO Cells

Publications

Multicopy Targeted Integration for Accelerated Development of High-Producing Chinese Hamster Ovary Cells

  • Sergeeva D, Lee GM, Nielsen LK, Grav LM ,

  • ACS Synth Biol ,

  • 2020,

  • 9(9):2546-2561

  • Instrument: NucleoCounter® NC-250™
  • Cell Type: CHO Cells
  • Assay: Cell Count & Viability Assay

The ever-growing biopharmaceutical industry relies on the production of recombinant therapeutic proteins in Chinese hamster ovary (CHO) cells. The traditional timelines of CHO cell line development can be significantly shortened by the use of targeted gene integration (TI). However, broad...

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