Webinars
ChemoMetec is proud to bring you upcoming webinars and recordings from previous webinars! Join us to pick up techniques and strategies that will help you to optimize laboratory workflow and avoid common pitfalls.
Our Application Scientists will discuss a wide range of topics in their webinars, including cell aggregation, consistency in cell counting, bioreactor optimization, viability dyes, and measuring cell death.
Upcoming webinars
Webinar: The art of upscaling – from processes to manufacturing in cell and gene therapy
Presenter:
- Matthew Smart, PhD, Senior Scientist at Cell and Gene Therapy Catapult
- James Kusena, PhD, Head of Bioprocessing at MicrofluidX
- Annemieke Karyotis, PhD, Field Application Scientist at ChemoMetec
In this webinar you’ll learn:
- Best practice in preparing an ATMP process for clinical manufacturing
- How Catapult helps to remove barriers to industrialisation of ATMP manufacturing
- Understanding of the R&D to manufacturing translation process
- Insight into a microfluidics-based technology for seamless upscaling
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Previous webinars
Webinar: Why is trypan blue toxic and unsafe to use?
Presenter:
- Torsten Schultz Larsen, PhD, Lead Application Scientist
- Janny Marie Peterslund, PhD, Scientific Affairs Manager
Do you know the pitfalls of trypan blue?
Aside from being toxic, trypan blue can cause issues with your cell counting. Join our webinar to find out why we recommend avoiding this cell viability dye.
In this webinar you’ll learn:
- How does exposure to trypan blue affect viable cells?
- How is the cell population viability underestimated?
- How does the viability analysis change over time?
- What are the alternatives?
Science Talk: Fast-tracking of a COVID-19 vaccine development
Presenter:
- Max M Søgaard, PhD, Vice President at ExpreS2ion Biotechnologies.
- Ali Salanti, PhD, Professor of Translational Microbiologi; Founder & Board Member at AdaptVac
- Louise Leth Hefting, PhD, Field Application Scientist at ChemoMetec A/S
- Janny Marie L Peterslund, PhD, Scientific Affairs Manager at ChemoMetec A/S
Join us for this Science Talk with Drs. Ali Salanti, Max M Søgaard, and Louise Leth Hefting on development of a virus-like particle (VLP)-based COVID-19 vaccine and what the companies behind it, AdaptVac and ExpreS2ion Biotechnologies, have done to fast-track their developmental pipeline.
In this science talk you’ll learn:
- Learn about the VLP and ExpreS2 technologies
- Get the insights on fast-tracking a COVID-19 vaccine
- What did AdaptVac and EspreS2ion learn through this developmental work?
- How did they work with industry partner ChemoMetec?
- What are Salanti and Søgaard’s take on the COVID-19 vaccine landscape?
Are sticky cells stickying up your data?
Presenter:Annemieke Karyotis, PhD / Field Application Scientist and Jonas la Cour, Head of Scientific Support
In this webinar, you’ll be equipped to recognize cellular aggregation and the difficulties it can pose in your research.We’ll examine the steps you can take to address clumping caused by these clusters to give you a few new tools to accelerate your research in the lab.Finally, we’ll propose real world solutions to help you become unglued from sticky cell results.In this webinar, you will:
- Be equipped to recognize cellular aggregation
- Discover how to count aggregated cells accurately and precisely
- Be invited to ask our scientific team questions in the Q&A
Are aggregated cells “stickying” up your data? How to break apart aggregated cells
Presenter: Greg Fendley, PhD / Senior Field Application Scientist
Cellular aggregation is one of the most ubiquitous challenges faced in the field of cell biology and can stand in the way of acquiring accurate, repeatable data.
In this webinar, we take a close look at:
- Cellular aggregation and the problems it can create for your research
- The causes in both culture and at the molecular level by taking a glance at the cell membrane
- Explore how your cell type and culture method may play a role in causing cell aggregation
- Prevention methods and practical applications for breaking-up cell aggregates and ways to incorporate this into reliable cell counting
- By watching, you will be well-equipped to recognize cellular aggregation, the dangers it may have on your instrumentation, and the traps it may lay during your data analysis
Consistency is King! Methods and techniques for getting the most consistent cell count
Presenter: Rodney Jarvis, PhD / Lead Application Scientist
Inconsistencies in cell therapy manufacturing can result in product release delays and a loss of time and resources. This can be avoided by identifying sources of variation early on in workflow development.
In this webinar, we uncover:
- Sources of variation in different sampling and quantification methods
- How small procedural inconsistencies can lead to significant discrepancies in downstream results
- Solutions, strategies and best practices to help eliminate sources of variation and how well these approaches translate to various types of cell counting
- The pros and cons of different cell counting methods
- The features that make a cell counter reliable, consistent and most suitable for cell therapy manufacturing
Scaling your cell culture system: Optimizing bioreactor conditions
Presenter: Alex Woychek, PhD / Field Application Scientist
Is your therapeutic application ready for scaling, but you’re not sure where to start? There are a lot of things to consider when expanding your cell culture system to a bioreactor.
This webinar covers:
- Culturing conditions in bioreactors for the following applications: stem cells, monoclonal antibodies and vaccine development
- The pros and cons of different bioreactor systems
- Issues to be on the look-out for
- Strategies for optimization
- Advances in the field
- Different types of microcarriers
- Best practices for monitoring the health and growth of your cell culture system through automated cell counting
Accurately measuring cell viability: Are all viability dyes created equal?
Presenter: Jeff Kremer, PhD / Field Application Scientist
Are all viability dyes created equal? The answer may surprise you… There is a wide range of detection methods and biochemical principles behind the function of viability dyes that can impact your data. From trypan blue to several different fluorescent dyes.
In this webinar we:
- Give an overview of the classification and practicality behind commonly used viability dyes based on measurement techniques, exclusion principles, and their use in automated cell counting
- Take an in-depth look at each dyes’ composition
- How each dye interacts with cells
- The pros and cons associated with the dyes’ laboratory use
Dead or alive? Is viability alone enough?
Presenter: Greg Fendley, PhD / Senior Field Application Scientist
A reliable cell count and viability is critical to the development and release of cell therapy products.
In this webinar we look at:
- The history of cell therapy, how it has emerged as a driver in the biopharma industry
- Factors to consider when assessing the overall health and viability of a cell therapy product
- Different modes of cell death, describe the pathways involved and identify the systematic events that lead a cell to the point of no return
- Automated methods and cell-based assays to measure these events and reveal how dying cells may initially register as viable, yet become functionally dead in downstream processes
The meticulous researcher’s guide to validating a cell counting method
Presenter: Annemieke Karyotis, PhD / Field Application Scientist, ChemoMetec
Do your cell counts vary at high and low concentrations? Is there too much variation between operators?
Like any methodology used in the laboratory, it’s important to validate and demonstrate that the cell counting method of choice is precise. But finding the correct methodology for testing this can be challenging, depending on the process and the sample type. This is why we’ve put this webinar together.
In this webinar, you’ll learn:
- How to choose an effective cell counting method
- Methods to measure the preciseness of your cell count
- The effect of process steps in cell counting (beads, red blood cells, transfection)
- How to understand the source of variation in cell counting
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