Webinars

ChemoMetec is proud to bring you our first ever webinar series! Join us to pick up techniques and strategies that will help you to optimize laboratory workflow and avoid common pitfalls.

Our Application Scientists will discuss a wide range of topics in their webinars, including cell aggregation, consistency in cell counting, bioreactor optimization, viability dyes, and measuring cell death.

Are aggregated cells “stickying” up your data? How to break apart aggregated cells

Presenter: Greg Fendley, PhD / Senior Field Application Scientist

Cellular aggregation is one of the most ubiquitous challenges faced in the field of cell biology and can stand in the way of acquiring accurate, repeatable data.

In this webinar, we take a close look at:

• Cellular aggregation and the problems it can create for your research
• The causes in both culture and at the molecular level by taking a glance at the cell membrane
• Explore how your cell type and culture method may play a role in causing cell aggregation
• Prevention methods and practical applications for breaking-up cell aggregates and ways to incorporate this into reliable cell counting
• By watching, you will be well-equipped to recognize cellular aggregation, the dangers it may have on your instrumentation, and the traps it may lay during your data analysis

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Consistency is King! Methods and techniques for getting the most consistent cell count

Presenter: Rodney Jarvis, PhD / Lead Application Scientist

Inconsistencies in cell therapy manufacturing can result in product release delays and a loss of time and resources. This can be avoided by identifying sources of variation early on in workflow development.

In this webinar, we uncover:

• Sources of variation in different sampling and quantification methods
• How small procedural inconsistencies can lead to significant discrepancies in downstream results
• Solutions, strategies and best practices to help eliminate sources of variation and how well these approaches translate to various types of cell counting
• The pros and cons of different cell counting methods
• The features that make a cell counter reliable, consistent and most suitable for cell therapy manufacturing
  

Scaling your cell culture system: Optimizing bioreactor conditions

Presenter: Alex Woychek, PhD / Field Application Scientist

Is your therapeutic application ready for scaling, but you’re not sure where to start? There are a lot of things to consider when expanding your cell culture system to a bioreactor.

This webinar covers:

• Culturing conditions in bioreactors for the following applications: stem cells, monoclonal antibodies and vaccine development
• The pros and cons of different bioreactor systems
• Issues to be on the look-out for
• Strategies for optimization
• Advances in the field
• Different types of microcarriers
• Best practices for monitoring the health and growth of your cell culture system through automated cell counting

Accurately measuring cell viability: Are all viability dyes created equal?

Presenter: Jeff Kremer, PhD / Field Application Scientist

Are all viability dyes created equal? The answer may surprise you… There is a wide range of detection methods and biochemical principles behind the function of viability dyes that can impact your data. From trypan blue to several different fluorescent dyes.

In this webinar we:

• Give an overview of the classification and practicality behind commonly used viability dyes based on measurement techniques, exclusion principles, and their use in automated cell counting
• Take an in-depth look at each dyes’ composition
• How each dye interacts with cells
• The pros and cons associated with the dyes’ laboratory use

Dead or alive? Is viability alone enough?

Presenter: Greg Fendley, PhD / Senior Field Application Scientist

A reliable cell count and viability is critical to the development and release of cell therapy products.

In this webinar we look at:

• The history of cell therapy, how it has emerged as a driver in the biopharma industry
• Factors to consider when assessing the overall health and viability of a cell therapy product
• Different modes of cell death, describe the pathways involved and identify the systematic events that lead a cell to the point of no return
• Automated methods and cell-based assays to measure these events and reveal how dying cells may initially register as viable, yet become functionally dead in downstream processes