Consistent yeast cell count & viability
The NucleoCounter® automated cell counter determines the cell count and viability with essential precision and reliability for brewers. The instrument provides the user with a fast, objective and high-precision measurement of yeast count and viability. The unique cassette-based sampling devices ensure easy handling and eliminate human subjectivity, resulting in very high accuracy and precision.
Application of the NucleoCounter® in brewing
The NucleoCounter® provides a quick and easy way to monitor yeast cell concentration while determining viability. It can analyze a volume more than three times greater than the volume commonly analyzed when manual cell counting. As a result, this feature makes the NucleoCounter® one of the leading automated cell counters for precision and accuracy on the market. The NucleoCounter® can provide a fast and accurate DNA-based volumetric cell count within seconds, independent of debris or substrate aggregates in the medium.
This system uses disposable sampling devices, the NucleoCassette™ and the Via2-Cassette™, which are pre-loaded with fluorescent dyes to detect and quantify total and viable cell populations. Because the NucleoCounter® detects signals from stained nuclei and does not rely on the visualization of the whole cell, the system operates without regard to cell size or morphology.
A newer instrument, the NucleoCounter® NC-202™, collects additional data parameters and is suited for more complex samples or when detailed studies are required. Furthermore, the NC-202™ comes with GMP-compliant software, enabling superior data management. The YC-100™ uses the NucleoCassette™ sampling device, and the NC-202™ uses the Via2-Cassette™.
Newly popular brew productions in the beverage and food industries besides beer include kombucha, kefir, kvass, root beer, nutritional supplements such as probiotics, yeast extract and vitamins.
Non-consumer products include bioethanol for energy production as well as for bioremediation of toxic or non-toxic waste and by-products of many industries.
Application of the NucleoCounter® in production runs
The endomembrane system of Saccharomyces cerevisiae makes it a cost-efficient alternative for producing proteins requiring posttranslational modifications.
Many biomedical production facilities use genetically modified yeast species as bio-factories to produce proteins, including insulin and other hormones, antigens for vaccines, and blood factors.
The NucleoCounter® NC-202™ provides the most precise and consistent yeast cell counting instrument for continuous monitoring of success criteria in production runs.
The unique Via2-Cassette™ ensures safe and easy handling of samples and eliminates human errors, for both experienced and new users.